Diosmin & Hesperidin
Rated 4.8 | 1,247 verified reviews
Locked Out of HRT?
Your Veins Didn't Get the Memo.
Doctors across Europe recommend the 90/10 Diosmin-Hesperidin ratio found in European prescription medicine. Unchanged for 30 years.
Doctor-Recommended Across Europe
The Diosmin and Hesperidin 90/10 ratio has been prescribed in Europe for over 30 years.
- Prescription medicine in many European countries
- Same molecules, same 90/10 ratio used in the research
- Backed by decades of clinical evidence for vein health and hemorrhoids
900mg Diosmin + 100mg Hesperidin in every daily dose: vein support for the chapter nobody gave you a plan B for. Not a hormone. Two citrus flavonoids, nothing else.
📄 See the full label + the one-page pharmacist sheet ↓- A plan B for your veinsThe HRT door closed. Your legs still deserve a daily routine.
- Not a hormoneTwo citrus flavonoids. Show this label to your doctor or pharmacist before you start.
- The classic 90/10 ratio900/100 printed on the label. No blends, no hidden doses.
- 99 days to decideJudge it over a whole season. Most customers feel relief within 21 days.
Two capsules a day with breakfast
For your pharmacist
The full label and the one-page pharmacist sheet
You've been told no before. Bring this page, ask once, and decide with the full picture.
The label
| Per daily serving (2 capsules) | Amount |
|---|---|
| Diosmin | 900 mg |
| Hesperidin | 100 mg |
The classic 90/10 ratio, full dose printed on the bottle. No proprietary blend, no hidden amounts. 30 days per bottle. Take 2 capsules a day with breakfast.
One-page sheet: please review before I start
Product: Vital Rems Diosmin 900 mg + Hesperidin 100 mg (90/10 ratio), dietary supplement.
How it's taken: 2 capsules once a day with breakfast. 30 days per bottle.
What it's for: daily support for veins and the slow, evening-heavy leg swelling. Not a treatment for clots, not hormone therapy, not a replacement for any prescribed medicine.
Please check against my medicines:
- Blood thinners (anticoagulants or antiplatelets): a possible bleeding risk with diosmin has been flagged by Health Canada.
- Any daily prescription I take: ____________________
- History of blood clots: yes / no Planned surgery: yes / no
My questions: Is it okay with my current medicines? Should my hematologist or doctor know? Anything I should watch for?
I'll keep every prescribed medicine and follow-up as is.
See a doctor today if
One leg is suddenly bigger, red, warm or painful. Shortness of breath or chest pain: call 911. Swelling past the knees, rapid weight gain, or skin that's broken or weeping. If you've had a clot before, you know your own warning signs: trust them.
✔ Verified buyerMy wife was told no to hormones and asked me to post this for her. Its literally two capsules with breakfast. Five weeks in and she says her legs feel lighter by evening.
Brian H. · Columbus, OH · 3 weeks agoWhy the "no" came without a plan
You were told no to HRT. Your veins didn't get the memo.
The no to hormones may be exactly right for you. Keep your doctor and your plan. But everything you've been offered since is for the flashes, the mood or the sleep.
Nobody checked on your veins. Think of scaffolding taken down from a building: the support that used to be there is gone, and the vein wall in your legs carries more of the load. This is not HRT and not a replacement for it. It's just the vein chapter, and why more women add a simple daily routine from the inside.
Customer reviews
What former hemorrhoid sufferers say
✔ Verified buyerSince my doctor said no to HRT every product i was sold was for hot flashes. Nobody mentioned my legs. My doctor looked at the label, and since taking these daily my evenings feel easier.
Lorraine K. · Tampa, FL · 1 month agoWhat's inside
Two citrus flavonoids. Nothing else.
Diosmin is a flavonoid naturally found in citrus fruit, and one of the most researched flavonoids in Europe.
Hesperidin is its natural partner: the flavonoid that gives orange peel its color.
Together, in the 90/10 ratio, they form a pairing that has been popular across Europe for decades. We use 900mg + 100mg per daily dose and print it on the label.
✔ Verified buyerI read every label now after wasting money on blends that wont tell you whats in them. 900mg and 100mg, right there on the bottle. Thats why i trusted it, and thats why i kept going.
Jennifer D. · Denver, CO · 2 weeks agoDecades of European use
A household name across Europe. Almost unknown in the US.
In France, Italy and much of Central Europe, the 90/10 diosmin-hesperidin pairing has been a familiar part of the pharmacy shelf for over 30 years.
In the US, almost nobody has heard of it. That gap is the reason this product exists.
✔ Verified buyerShe has taken diosmin for years back home, its just normal there. Over here nobody had ever mentioned it to me, not even the pharmacist. Wish id asked her sooner.
Rachel T. · San Diego, CA · 1 month agoYour first 99 days
How the routine works
Two capsules with breakfast. That's the whole routine.
The habit is set. Keep it daily. Consistency is the whole point.
Three weeks in: most customers feel relief by now. Time for your first honest check-in.
Six weeks of routine. Keep going: the support builds the longer you stay consistent.
Your guarantee checkpoint. Not happy with the change? Every cent back, empty bottles and all.
✔ Verified buyerI checked the days off on the fridge calendar because i honestly didnt expect much. Somewhere around the third week i noticed i'd gone a whole day without that nagging discomfort.
Mandy S. · Raleigh, NC · 3 weeks agoThe difference
With it vs without it
With a daily inside-out routine
- Something working on the vein wall every day
- Two capsules with breakfast. Hormone-free
- A routine you can keep for months, not minutes
- Full transparency: dose and ratio on the label, to show your doctor
Without it
- Heavy legs nobody asks about
- The same tired evenings, on a schedule you know by heart
- Nothing working on the vein wall
- Mystery blends with hidden doses
✔ Verified buyerIm on my feet all day at the store and by afternoon my legs felt like lead. Two months on these and i can do a full shift without that heavy ache.
Kevin P. · Phoenix, AZ · 2 months agoSide by side
How it compares
 This formula |  Gels |  Spot fixes |  Soaks | |
|---|---|---|---|---|
| Daily routine from the inside | ✓ | ✕ | ✕ | ✕ |
| 90/10 diosmin-hesperidin ratio | ✓ | ✕ | ✕ | ✕ |
| Designed for daily, long-term use | ✓ | ✕ | ✕ | ✕ |
| Dose verified per batch | ✓ | ✕ | ✕ | ✕ |
| Useful for short-term surface comfort | ✕ | ✓ | ✓ | ✓ |
✔ Verified buyerThe Amazon ones never said how much was actually in them and did nothing for me. This one has the full dose and the 90/10 ratio on the label. Wish id started here.
Paul R. · Indianapolis, IN · 1 month agoBefore you buy
Four questions to ask before buying ANY diosmin product
If the answer to any of these is no, you don't really know what you're taking.
✔ Verified buyerAt 67 i thought id tried everything. What got me was the 99 day guarantee, nothing to lose. Three bottles later i can garden all morning and actually enjoy it.
Margaret L. · Sarasota, FL · 5 weeks agoQuestions
Frequently asked questions
Is this a replacement for HRT?
No. It isn't a hormone and it isn't HRT. It doesn't do anything for hot flashes, mood or sleep. It's daily support for your veins only. Show this label to your doctor or pharmacist before you start.
I was told no to hormones because of a clot risk. Can I take this?
Show this label (diosmin 900 mg + hesperidin 100 mg daily) to your doctor or pharmacist before you start, especially if you take blood thinners. Don't start or stop any medication on your own.
Can I take it with my medications?
Diosmin may interact with some medications. Show this label to your doctor or pharmacist before you start, especially if you take blood thinners (anticoagulants or antiplatelets): a possible bleeding risk has been flagged by Health Canada. Stop taking it before any planned surgery, and never adjust a prescribed medication on your own.
When should I see a doctor first?
Right away (call 911 for chest pain or trouble breathing) if one leg suddenly swells, turns red, warm or painful, or if you have chest pain or shortness of breath. This is a daily support routine, not a diagnosis. Check first. Then support.
How long before I notice anything?
Weeks, not days. Most women judge it by how their legs feel at the end of the day over their first few weeks. Take it every day and give it at least 21 days. With the 99-day guarantee, you have plenty of time to decide.
Why isn't it at CVS, Walgreens or on Amazon?
We sell direct, so we can keep the price fair and honor the 99-Day Empty-Bottle Guarantee ourselves. And the cheap look-alikes on Amazon often skip what matters: the full 900mg/100mg dose, the 90/10 ratio and third-party testing. Only buy it here.
Risk reversal
The 99-Day Empty-Bottle Guarantee
Take it daily for up to 99 days. If you're not genuinely happy with the difference, email us and you get a full refund. No need to return anything, no questions, no forms. The risk is on us, where it belongs.
- Full refund
- No need to return the bottle
- Tracked US shipping